Enhancing the security, autonomy, and controllability of the earthquake core business systems is of great significance to national security. Based on the localization migration and adaptation of the earthquake core business systems, the localization alternative solution using C86 and ARM technology architectures, Haiguang and Kunpeng servers, Kylin V10 operating system, Dongfangtong middleware, and VastBase database as the operating environment was selected after comparison. Compared with the foreign product solution under the X86 architecture using Huawei application servers, Intel CPUs, Mysql database, FreeBSD operating systems, and Wildfly and Tomcat middleware as the operating environment,the localization alternative solution is equivalent in function and performance, meeting the needs of business use in the earthquake industry. It provides a valuable reference for innovative practice in the subsequent comprehensive localization substitution work of the earthquake industry.