The online video open course of earthquake prevention and disaster reduction in schools can provide open educational resources of earthquake knowledge for teachers and students. Based on the demand of the online video open course of earthquake prevention and disaster reduction, this paper introduces the production and promotion of the online video open course of earthquake prevention and disaster reduction of Yunnan Earthquake Agency, summarizes the problems in the practice process and puts forward some thinking for the next step:Work preparation, such as script optimization design and trial presentation organization, can reduce the later video modification. By means of heuristic presentation, action demonstration, test questions, etc., it can make up for the shortcomings of unilateral knowledge imparting of online video open course. The paper tries to cooperate with major learning platforms, broaden the platform delivery, improve the efficiency of use, and achieve the purpose of publicity.